PF-06952229, CAS 1801333-55-0

Product Description: PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction.?PF-06952229 is a promising antineoplastic?agent for the study solid tumors, especifically metastatic breast cancer[1].

Applications: Cancer-Kinase/protease

Formula: C23H24ClFN4O3

References: [1]Flavia Mercer Pernasetti, et al. Combinations of tgfb inhibitors and cdk inhibitors for the treatment of breast cancer. Patent WO2020058820A1.

CAS Number: 1801333-55-0

Molecular Weight: 458.91

Compound Purity: 99.92

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: TGF-β Receptor

• SKU: MEXHY-136244-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136244-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK