PF-6274484, CAS 1035638-91-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide

Purity: ≥98%

Formula Markup: C18H14ClFN4O2

Formula Weight: 372.8

CAS Number: 1035638-91-5

Notes: PF-6274484 is an inhibitor of the EGF receptor (EGFR; IC50s = 0.18 and 0.14 nM for wild-type EGFR and inhibitor-resistant EGFRL858R/T790M, respectively).{36569} It inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells (IC50s = 5.8 and 6.6 nM, respectively).

• SKU: CAY22698-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22698-1
• Package Unit: 1 mg
• Quantity Unit: STK