Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N-phenyl-4-(quinolin-2-ylmethyl)piperidine-1-carboxamide
Purity: ≥98%
Formula Markup: C22H23N3O
Formula Weight: 345.4
CAS Number: 959151-50-9
Notes: Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PF-750 is a potent, time-dependent, irreversible FAAH inhibitor with IC50 values of 0.6 and 0.016 µM when preincubated with recombinant human FAAH for 5 and 60 minutes, respectively.{15092} Activity-based profiling of various human and murine tissue proteome samples revealed that PF-750 is highly selective for FAAH relative to other serine hydrolases, showing no discernable off-site activity up to 500 µM.{15092}