PFM01, CAS 1558598-41-6

Product Description: PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR)[1][2].

Applications: Cancer-programmed cell death

Formula: C14H15NO2S2

References: [1]Shibata A, et, al. DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol Cell. 2014 Jan 9; 53(1): 7-18./[2]Völkening L, et, al. RAD50 regulates mitotic progression independent of DNA repair functions. FASEB J. 2020 Feb; 34(2): 2812-2820.

CAS Number: 1558598-41-6

Molecular Weight: 293.40

Compound Purity: 99.68

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL/Ethanol : 25 mg/mL (ultrasonic)

Target: Endonuclease

• SKU: MEXHY-116770-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-116770-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK