Phe-Arg-βNA (hydrochloride), CAS 100929-99-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: L-phenylalanyl-N-2-naphthalenyl-L-argininamide, dihydrochloride

Purity: ≥98%

Formula Markup: C25H30N6O2 / 2HCl

Formula Weight: 519.46622

CAS Number: 100929-99-5

Notes: Phe-Arg-βNA is a peptide broad-spectrum bacterial efflux pump inhibitor.{53463} It potentiates the activity of the fluoroquinolone antibiotic levofloxacin (Item No. 20382) against P. aeruginosa strains overexpressing the MexAB-OprM, MexCD-OprJ, or MexEF-OprN multidrug resistance efflux pumps (EC50s = 10 µg/ml for all) but is inactive against these strains when used alone (MICs = >512 µg/ml for all). Phe-Arg-βNA also increases the susceptibility of quinolone-resistant E. coli isolates to nalidixic acid (Item No. 19807).{53464}

• SKU: CAY29511-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29511-100
• Package Unit: 100 mg
• Quantity Unit: STK