PI4KIII beta inhibitor 5, CAS 3029506-23-5

Product Description: PI4KIII beta inhibitor 5 is a PI4KIIIβ inhibitor with an IC50 of 19 nM. PI4KIII beta inhibitor 5 can induce cancer cell apoptosis (Apoptosis), cell cycle arrest at the G2/M phase, and autophagy (Autophagy) by inhibiting the PI3K/AKT pathway. PI4KIII beta inhibitor 5 has also demonstrated significant antitumor activity in the H446 xenograft model of small cell lung cancer. PI4KIII beta inhibitor 5 can be used for research in the field of cancer therapy[1].

Formula: C24H27F2N3O4S2

References: [1]Wang B, et al. Discovery of 5-Phenylthiazol-2-amine Derivatives as Novel PI4KIIIβ Inhibitors with Efficacious Antitumor Activity by Inhibiting the PI3K/AKT Axis. J Med Chem. 2025 Mar 6.

CAS Number: 3029506-23-5

Molecular Weight: 523.62

Research Area: Cancer

Target: PI4K

• SKU: MEXHY-172256-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172256-0
• Package Unit: Get quote
• Quantity Unit: STK