Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N,N'-[[(2R,5R)-1-[3,5-difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]phenyl]-2,5-pyrrolidinediyl]bis[(6-fluoro-1H-benzimidazole-5,2-diyl)-(2S)-2,1-pyrrolidinediyl[(1S)-1-[(1R)-1-methoxyethyl]-2-oxo-2,1-ethanediyl]]]bis-carbamic acid, dimethyl ester
Purity: ≥98%
Formula Markup: C57H65F5N10O8
Formula Weight: 1113.180616
CAS Number: 1353900-92-1
Notes: Pibrentasvir is an inhibitor of hepatitis C virus (HCV) non-structural protein 5A (NS5A).{51095} It inhibits HCV replication in stable replicon cell lines containing NS5A from genotypes 1-6 (EC50s = 1.4-4.3 pM). Pibrentasvir acts synergistically with the HCV NS3/4A protease inhibitor glecaprevir to inhibit HCV genotype 1b-Con1 replication in replicon cells.{51096} Formulations containing pibrentasvir have been used in combination with glecaprevir in the treatment of HCV infection.
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