PNU 74654, CAS 113906-27-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-phenoxy-benzoic acid, 2-[(5-methyl-2-furanyl)methylene]hydrazide

Purity: ≥98%

Formula Markup: C19H16N2O3

Formula Weight: 320.3

CAS Number: 113906-27-7

Notes: The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers.{26669} PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.{26667} Treatment of human adrenocortical cell lines with PNU 74654 significantly reduced expression of several Tcf/β-catenin target genes.{26670}

• SKU: CAY16349-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 16349-10
• Package Unit: 10 mg
• Quantity Unit: STK