PNU112455A (hydrochloride), CAS 21886-12-4

Product Description: PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C10H12ClN5O2S

References: [1]Clare PM, et al. The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. J Biol Chem. 2001 Dec 21;276(51):48292-9.

CAS Number: 21886-12-4

Molecular Weight: 301.75

Compound Purity: 99.56

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)/H2O : 20 mg/mL (ultrasonic)

Target: CDK

• SKU: MEXHY-112468-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112468-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK