Polmacoxib, CAS 301692-76-2

Description: Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.

CAS Number: 301692-76-2

Formula: C18H16FNO4S

Molecular Weight: 361,39

References: Kim SH, Margalit O, Katoh H,et al. CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models. Invest New Drugs. 2014 Aug 3. [Epub ahead of print] PubMed PMID: 25085205.

• SKU: TGMT21294-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T21294-1mL
• Package Unit: 1 mL
• Quantity Unit: STK