Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N-(4-amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide sulfate
Purity: ≥80% (B Polymyxins)
Formula Markup: C56H98N16O13 / H2SO4
Formula Weight: 1301.6
CAS Number: 1405-20-5
Notes: The polymyxins are cationic peptides originally isolated from B. polymyxa.{22080} They bind and kill Gram-negative bacteria.{22081} The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B (sulfate) is a mixture of at least four closely related components, polymyxin B1 to B4, with polymyxin B1 (Item No. 14074) and B2 being the two major components.{22082,22304} Polymyxin B (sulfate) has rapid in vitro bactericidal activity against major multidrug-resistant Gram-negative bacteria, such as P. aeruginosa, A. baumannii, and K. pneumoniae.{22304}
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