Product Type: Inhibitor
CAS No.: 19171-19-8
MolecularFormula: C13H11N3O4
Molecular Weight: 273,2
Source: Synthetic
Purity: >98% (TLC); NMR (Conforms)
Solubility: May be dissolved in DMSO (50 mg/ml)
Appearance: Yellow powder
PubChem CID: 134780
Scientific Background: Pomalidomide, a derivative of thalidomide, is an inhibitor TNF-α production (1), enhances the activity of T cells and natural killer cells and enhances antibody- dependent cellular cytotoxicity. It also may inhibit tumor angiogenesis, and promote cell cycle arrest (2).
References: 1. D'Amato R., Lentzsch S, Anderson K.C. ad Rogers M.S. (2001) Seminars in Oncology. 28(6): 597-601. 2. Fujiwara Y., et al. (2018) Cancer Research. DOI: 10.1158/0008-5472.CAN-18-1781
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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