PP58, CAS 212391-58-7

Product Description: PP58 is a pyrido[2,3-d]pyrimidine-based compound that inhibits PDGFR, FGFR and Src family activities with nanomolar IC50 values.

Applications: Cancer-Kinase/protease

Formula: C22H19Cl2N5O2

References: [1]Wissing J, et al. Chemical Proteomic Analysis Reveals Alternative Modes of Action for Pyrido[2,3-d]pyrimidine Kinase Inhibitors. Mol Cell Proteomics. 2004 Dec;3(12):1181-93./[2]Blencke S, et al. Characterization of a conserved structural determinant controlling protein kinase sensitivity to selective inhibitors. Chem Biol. 2004 May;11(5):691-701.

CAS Number: 212391-58-7

Molecular Weight: 456.32

Compound Purity: 99.75

Research Area: Cancer

Solubility: DMSO : 62.5 mg/mL (ultrasonic)

Target: FGFR;PDGFR;Src

• SKU: MEXHY-18622-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18622-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK