Recombinant Human CRTAM Protein(His Tag)

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Protein Tag: C-His

Uniprot: O95727

Accession: O95727

Background: The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A, MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Bio Acitivity: Not validated for activity

Sequence: Ser18-Gly287

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 29.5 kDa

Observed MW: 55-65 kDa

• SKU: ELSPDMH100222-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100222-1
• Package Unit: 1 mg
• Quantity Unit: STK