Recombinant Human ICAM5 Protein(His Tag)

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Protein Tag: C-His

Uniprot: Q9UMF0

Accession: Q9UMF0

Background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

Bio Acitivity: Not validated for activity

Sequence: Glu32-Trp835

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 88.3 kDa

Observed MW: 100-120 kDa

• SKU: ELSPDMH100224-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100224-1
• Package Unit: 1 mg
• Quantity Unit: STK