Recombinant Human SNCα Protein(Trx Tag)

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Protein Tag: N-Trx

Uniprot: P37840

Accession: P37840

Background: Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson"s Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).

Bio Acitivity: Not validated for activity

Sequence: Met1-Ala140

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method

Calculated MW: 35.2 kDa

Observed MW: 37 kDa

• SKU: ELSPDEH101110-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDEH101110-1
• Package Unit: 1 mg
• Quantity Unit: STK