Recombinant Mouse Interleukin-2/IL-2 Protein (active)

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Target Synonym: Interleukin-2;IL-2;T-Cell Growth Factor;TCGF;Aldesleukin

Background: Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.

Bio Activity: Measured in a cell proliferation assay using HT-2 mouse T cells. The ED50 for this effect is 0.88-3.5 ng/mL, corresponding to a specific activity of 2.86×105-1.14×106 units/mg.

Sequence: Ala21-Gln169

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Calculated MW: 18.07 kDa

Observed MW: 22-25 kDa

• SKU: ELSPKSM041523-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PKSM041523-20
• Package Unit: 20μg
• Quantity Unit: STK