Recombinant Rat IL-4 Protein(Trx Tag)

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Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Synonym: Interleukin-4;B-cell stimulatory factor 1;BSFR-1

Protein Tag: N-Trx

Background: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

Bio Activity: Not validated for activity

Sequence: Cys25-Ser147

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Calculated MW: 33.4 kDa

Observed MW: 33 kDa

• SKU: ELSPDER100244-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDER100244-1
• Package Unit: 1 mg
• Quantity Unit: STK