PRT-060318, CAS 1194961-19-7

Product Description: PRT-060318 (PRT318) is a novel selective inhibitor of the tyrosine kinase Syk with an IC50 of 4 nM.

Applications: Cancer-Kinase/protease

Formula: C18H24N6O

References: [1]Reilly MP, et al. PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model. Blood. 2011 Feb 17;117(7):2241-6./[2]Hoellenriegel J, et al. Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration. Leukemia. 2012 Jul;26(7):1576-83.

CAS Number: 1194961-19-7

Molecular Weight: 340.42

Compound Purity: 99.04

Research Area: Cancer

Solubility: H2O : 25 mg/mL (ultrasonic)

Target: Syk

• SKU: MEXHY-12974-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12974-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK