Target Synonym: IL3RA;CD123;IL3R;IL3RAY;IL3RX;IL3RY;hIL-3Ra;IL-3 Receptor alpha;IL-3 receptor subunit alpha;IL-3R subunit alpha;IL-3R subunitalpha;IL-3RA;IL-3R-alpha;IL-3Receptoralpha;IL-3Rα;IL-4Receptoralpha;IL-5Receptoralpha;IL-6Receptoralpha;IL-7Receptoralpha;Interleukin-3 receptor subunit alpha;IL-3R&alpha
Background: CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Immunogen: Recombinant Human CD123 protein
Buffer: PBS, pH 7.2. Contains 0.05% proclin 300.
Dilution: FCM 2 μg/mL(1×105-5×105 cells)
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