Puxitatug samrotecan, CAS 2760250-80-2

Product Description: Puxitatug samrotecan (AZD8205) is an antibody-drug conjugate (ADC) targeting B7-H4. Puxitatug samrotecan is composed of the Puxitatug (HY-P990059) antibody targeting B7-H4, randomly conjugated to the Puxitatug samrotecan drug-linker (HY-163487) by reducing inter-chain cysteines. Puxitatug samrotecan has anti-tumor activity and can be used in the study of cancers expressing B7-H4[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Kinneer K,et al. Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305. Clin Cancer Res. 2023 Mar 14;29(6):1086-1101.

CAS Number: 2760250-80-2

Molecular Weight: N/A

Research Area: Cancer

Target: Antibody-Drug Conjugates (ADCs)

• SKU: MEXHY-171689-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171689-5
• Package Unit: 5 mg
• Quantity Unit: STK