QNZ 46, CAS 1237744-13-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[6-methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic acid

Purity: ≥98%

Formula Markup: C24H17N3O6

Formula Weight: 443.4

CAS Number: 1237744-13-6

Notes: QNZ 46 is an antagonist of NR2C- and NR2D-subunit containing NMDA receptors (IC50s = 6 and 3 µM, respectively, for receptors expressed in Xenopus oocytes).{38922} It is selective for NR2C- and NR2D-subunit containing NMDA receptors over receptors containing NR2A and NR2B subunits as well as over the AMPA receptor GluR1 (IC50s = 229, >300, and >300 µM, respectively). QNZ 46 acts in a noncompetitive and voltage-independent fashion that requires glutamate but not glycine binding for its activity.{38923}

• SKU: CAY14857-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 14857-5
• Package Unit: 5 mg
• Quantity Unit: STK