Product Description: Questin is an anthraquinone compound and antibacterial agent. Questin can be isolated from marine-derived fungi and plants. Questin inhibits Cdc25B phosphatase. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL. Questin displays antiprotozoal activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL. Questin has anticancer activity against lung and colon cancer[1][2][3][4][5].
Applications: COVID-19-immunoregulation
Formula: C16H12O5
References: [1]Lei Guo, et al. Optimized production and isolation of antibacterial agent from marine Aspergillus flavipes against Vibrio harveyi. 3 Biotech. 2017 Dec;7(6):383./[2]Choi SG, et al. Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb. Nat Prod Res. 2007 May 20;21(6):487-93./[3]Gauthier T, et al. Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells. PLoS One. 2012;7(2):e29906./[4]Liu N, et al. Structurally diverse sesquiterpenoids and polyketides from a sponge-associated fungus Aspergillus sydowii SCSIO41301. Fitoterapia. 2019 Jun;135:27-32./[5]Chaudhary NK, et al. Banksialactones and Banksiamarins: Isochromanones and Isocoumarins from an Australian Fungus, Aspergillus banksianus. J Nat Prod. 2018 Jul 27;81(7):1517-1526.
CAS Number: 3774-64-9
Molecular Weight: 284.26
Compound Purity: 97.75
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: Bacterial;Parasite;Phosphatase
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