QX-77, CAS 1798331-92-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[4-(7-chloro-2H-1,4-benzoxazin-3-yl)phenyl]-acetamide

Purity: ≥98%

Formula Markup: C16H13ClN2O2

Formula Weight: 300.7394

CAS Number: 1798331-92-6

Notes: QX-77 is an activator of chaperone-mediated autophagy (CMA).{48935} It decreases mouse embryonic fibroblast (MEF) and Neuro2a cell death induced by paraquat or oleic acid (Item Nos. 90260 / 24659). QX-77 (20 µM) rescues defective trafficking and lysosomal localization of the CMA receptor LAMP2A in Ctns-/- MEFs and CTNS knockout human proximal tubule cells, models of the lysosomal storage disorder cystinosis.{48936}

• SKU: CAY29903-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29903-50
• Package Unit: 50 mg
• Quantity Unit: STK