Product Description: (R)-Baclofen (Arbaclofen) is a selective GABAB receptor agonist[1].
Applications: Neuroscience-Neuromodulation
Formula: C10H12ClNO2
References: [1]Hong YG, et al. Effects of phaclofen and the enantiomers of baclofen on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat. Eur J Pharmacol. 1991 Apr 24;196(3):267-75./[2]Falch E, et al. Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J Neurochem. 1986 Sep;47(3):898-903./[3]Falch E, et al. Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J Neurochem. 1986 Sep;47(3):898-903./[4]Orsnes G, et al. The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients. Clin Neurophysiol. 2000 Aug;111(8):1372-9.
CAS Number: 69308-37-8
Molecular Weight: 213.664
Compound Purity: 99.50
Research Area: Neurological Disease; Cancer
Solubility: DMSO : 1 mg/mL (ultrasonic;warming;heat to 80°C)/H2O : 5 mg/mL (ultrasonic)
Target: GABA Receptor
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