Shelf life (days): 1460.0
Formulation: A solid
Formal Name: a-amino-3,5-dihydroxy-benzeneacetic acid
Purity: ≥98%
Formula Markup: C8H9NO4
Formula Weight: 183.1614
CAS Number: 146255-66-5
Notes: (R,S)-3,5-DHPG is an agonist of group I metabotropic glutamate receptors (mGluRs).{24133} It induces phosphoinositol hydrolysis in MCB3901, also known as AV12-664, cells expressing human mGluR1a and mGluR5a in a concentration-dependent manner. (R,S)-3,5-DHPG (10 µM) potentiates NMDA-induced depolarizations in rat hippocampal slices. Intrathecal administration of (R,S)-3,5-DHPG (300 nmol/animal) increases mean blood pressure in anesthetized rats.{68140} Intracerebroventricular administration of (R,S)-3,5-DHPG (1.5 µmol/animal) induces seizures in rats.{68141}