Product Description: (R,S,S)-VH032-Me is a ligand for E3 ubiquitin ligase. (R,S,S)-VH032-Me can be connected to the ligand for protein by a linker to form dTAGV-1-NEG (HY-145514A). PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Formula: C23H32N4O3S
References: [1]Nabet B, et al. Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nat Commun. 2020 Sep 18;11(1):4687.
CAS Number: 1948273-05-9
Molecular Weight: 444.59
Research Area: Cancer
Target: Ligands for E3 Ligase