(R)-Zanubrutinib, CAS 1691249-44-1

Product Description: (R)-Zanubrutinib is the R enantiomer of Zanubrutinib (HY-101474A). (R)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 11 nM.

Formula: C27H29N5O3

References: [1]Wu J, et al. Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor. J Hematol Oncol. 2016 Mar 9;9:21./[2]Wu J, et al. Second-generation inhibitors of Bruton tyrosine kinase. J Hematol Oncol. 2016 Sep 2;9(1):80.

CAS Number: 1691249-44-1

Molecular Weight: 471.55

Compound Purity: 98.97

Research Area: Others

Solubility: DMSO : ≥ 64.25 mg/mL

Target: Btk

• SKU: MEXHY-101474B-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101474B-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK