Rabbit anti-ATM Recombinant Monoclonal Antibody (BLR359N)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_000042.3

Uniprot ID: Q13315

Background: Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4.

Immunogen: between 2550 and 2600

• SKU: BEYA700-359
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-359
• Package Unit: 100 µl (50+ tests)
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotype: Whole IgG
• Human Gene ID: 472
• Host: Rabbit
• Conjugate: Unconjugated