Background: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
Positive Control: Human Hepatocellular Carcinoma.
Immunogen: Synthetic peptide derived from human HSF1 protein.
Purification Method: Antigen Immunoaffiinity Purification.
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.
References: 1. Jin, X., et al. ‘Targeted deletion of Hsf1, 2, and 4 genes in mice.’ Methods Mol. Biol., 787, 1-20 (2011)
2. Kaitsuka, T., et al. ‘Transformation of eEF1Bdelta into heat-shock response transcription factor by alternative splicing.’ EMBO Rep., 12, 673-681 (2011).
UniProt: Q00613.
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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