Background: Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain By similarity. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
Positive Control: Human adipose tissue.
Immunogen: Synthetic peptide derived from the human Monoglyceride Lipase protein.
Purification Method: Antigen Immunoaffiinity Purification.
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.
References: 1. Nomura, D.K., et al. ‘Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.’ Cell, 140, 49-61 (2010).
UniProt: Q99685.
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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