Rabbit anti-NUMB Antibody Affinity Purified

Stock Concentration: 200 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein Ref Seq ID: NP_001005743.1

Uniprot ID: P49757

Background: NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.

Immunogen: Between 375 and 425

Physical State: Liquid

Purity: Antigen Affinity Purified

Antibody Registry ID: AB_1211242

• SKU: BEYA301-714A-T
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A301-714A-T
• Package Unit: 10 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation, Western Blotting
• Isotype: IgG
• Human Gene ID: 8650
• Host: Rabbit
• Conjugate: Unconjugated