Rabbit anti-SF3b145/SAP145 Antibody Affinity Purified

Stock Concentration: 200 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein Ref Seq ID: NP_006833.2

Uniprot ID: Q13435

Background: SF3b145/SAP145 is a 145 kDa subunit of the splicing factor 3B (SF3B) protein complex. The SF3B complex is composed of at least 8 subunits (SF3B1 through SF3B8). SF3A along with SF3B and a 12S RNA unit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. In this complex SF3B2 interacts directly with SF3B4 and associates with the pre-mRNA upstream of the branch site at the anchoring site. SF3A and SF3B may play a role in anchoring the U2 snRNP to the pre-mRNA upstream of the intron’s branch site.

Immunogen: Between 845 and C-terminus

Physical State: Liquid

Purity: Antigen Affinity Purified

Antibody Registry ID: AB_1078828

• SKU: BEYA301-606A-T
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A301-606A-T
• Package Unit: 10 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotype: IgG
• Human Gene ID: 10992
• Host: Rabbit
• Conjugate: Unconjugated