Rabbit anti-STUB1/CHIP Antibody Affinity Purified

Stock Concentration: 200 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein Ref Seq ID: NP_005852.2

Uniprot ID: Q9UNE7

Background: STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimers and Down’s syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53.

Immunogen: Between 1 and 50

Physical State: Liquid

Purity: Antigen Affinity Purified

Antibody Registry ID: AB_1039992

• SKU: BEYA301-572A
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A301-572A
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Polyclonal
• Application: Immunoprecipitation, Western Blotting
• Isotype: IgG
• Human Gene ID: 10273
• Host: Rabbit
• Conjugate: Unconjugated