Rabbit anti-UVRAG Antibody Affinity Purified

Stock Concentration: 200 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein Ref Seq ID: NP_003360.2

Uniprot ID: Q9P2Y5

Background: UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.

Immunogen: Between 600 and 650

Physical State: Liquid

Purity: Antigen Affinity Purified

Antibody Registry ID: AB_1576604

• SKU: BEYA301-995A-T
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A301-995A-T
• Package Unit: 10 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation, Western Blotting
• Isotype: IgG
• Human Gene ID: 7405
• Host: Rabbit
• Conjugate: Unconjugated