Product Description: (rac)-Methyl jasmonate (Standard) is the analytical standard of Methyl jasmonate. This product is intended for research and analytical applications. (rac)-Methyl jasmonate is the racemate of Methyl jasmonate (HY-135663). Methyl jasmonate is a phytohormone that regulates the defense response of plants under biotic and biotic stress through jasmonate signaling pathway. Methyl jasmonate inhibits the activation of NF-κB signaling pathway. Methyl jasmonate can promote the mitochondrial ROS production, but also scavenges free radicals and reduces the oxidative stress. Methyl jasmonate exhibits anti-inflammatory, antitumor, anticonvulsant, antinociceptive and sedative activities[1][2][3][4][5][6].
Formula: C13H20O3
References: [1]Pereira-Maróstica HV, et al., Methyl Jasmonate Reduces Inflammation and Oxidative Stress in the Brain of Arthritic Rats. Antioxidants (Basel). 2019 Oct 15;8(10):485./[2]Yu X, et al., The roles of methyl jasmonate to stress in plants. Funct Plant Biol. 2019 Feb;46(3):197-212./[3]Tong QS, et al., Methyl jasmonate downregulates expression of proliferating cell nuclear antigen and induces apoptosis in human neuroblastoma cell lines. Anticancer Drugs. 2008 Jul;19(6):573-81./[4]Annafi OS, et al., Evaluation of the anticonvulsant and anxiolytic potentials of methyl jasmonate in mice. Sci Pharm. 2014 Mar 24;82(3):643-54./[5]Eduviere AT, et al., Methyl jasmonate enhances memory performance through inhibition of oxidative stress and acetylcholinesterase activity in mice. Life Sci. 2015 Jul 1;132:20-6./[6]Umukoro S, et al., Antinociceptive effects of methyl jasmonate in experimental animals. J Nat Med. 2011 Jul;65(3-4):466-70.
CAS Number: 39924-52-2
Molecular Weight: 224.30
Research Area: Cancer; Inflammation/Immunology; Neurological Disease
Target: Apoptosis;Glutathione Peroxidase;NF-κB;Phytohormone;Reactive Oxygen Species;Reference Standards
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