(Rac)-PF-4136309, CAS 857679-55-1

Product Description: (Rac)-PF-4136309 is an isoform of PF-4136309 (HY-13245), which is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.

Applications: COVID-19-immunoregulation

Formula: C29H31F3N6O3

References: [1]Xue CB, et al. Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist. ACS Med. Chem. Lett., 2011, 2 (12), pp 913-918.

CAS Number: 857679-55-1

Molecular Weight: 568.59

Compound Purity: 98.0

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: CCR

• SKU: MEXHY-13245B-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13245B-25
• Package Unit: 25 mg
• Quantity Unit: STK