(Rac)-VU 6008667, CAS 2092917-63-8

Product Description: (Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration[1].

Applications: Neuroscience-Neuromodulation

Formula: C24H17ClF2N2O2

References: [1]McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359.

CAS Number: 2092917-63-8

Molecular Weight: 438.85

Compound Purity: 99.85

Research Area: Neurological Disease

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: mAChR

• SKU: MEXHY-101281A-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101281A-25
• Package Unit: 25 mg
• Quantity Unit: STK