RAF709, CAS 1628838-42-5

Product Description: RAF709 is a potent, selective, and efficacious RAF inhibitor with IC50s of 0.4 nM and 0.5 nM for BRAF and CRAF, respectively[1]. Antitumor efficacy[1].

Applications: Cancer-Kinase/protease

Formula: C28H29F3N4O4

References: [1]Nishiguchi GA, et al. Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers. J Med Chem. 2017 Jun 22;60(12):4869-4881.

CAS Number: 1628838-42-5

Molecular Weight: 542.55

Compound Purity: 99.45

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Raf

• SKU: MEXHY-100510-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100510-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK