Raseglurant, CAS 757950-09-7

Product Description: Raseglurant (ADX-10059) is a mGlu5 receptor negative allosteric modulator. Raseglurant is effective against migraine. Raseglurant reduces the Haloperidol (HY-14538)-induced catalepsy in mice[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C15H13FN2

References: [1]Romero-Fernandez W, et al. The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease. Mol Neurobiol. 2022 Oct;59(10):5955-5969. /[2]Font J, et al. Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. Elife. 2018 Jan 8;7:e34752.

CAS Number: 757950-09-7

Molecular Weight: 240.28

Research Area: Neurological Disease

Target: mGluR

• SKU: MEXHY-14866-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14866-10
• Package Unit: 10 mg
• Quantity Unit: STK