Clone Number: IBL-3/25
Immunogen: mouse lymph node cells
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: IBL-3/25 is directed against the α-chain of CD8. The CD8 complex consists of a disulphide-linked α/β heterodimer with a MW of 30 kDa or an α/α homodimer with a MW of 32 kDa. The CD8 molecule binds to HLA class I molecules during interaction of CD8+ T-cells with antigenpresenting cells or with target cells. CD8+ T-cells include most of the cytotoxic T-cells.
Applications: FC, IHC-fr, IF
References: Knapp W. et. al. Leukocyte Typing IV, p342-343, (1989)/Parnes JR, Semin Immunol 6: 221-229 (1994)/Delon J. et al. Immunity 9(4): 467-73 (1998)