Rauwolscine (hydrochloride), CAS 6211-32-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (16ß,17a,20a)-17-hydroxy-yohimban-16-carboxylic acid, methyl ester, monohydrochloride

Purity: ≥98%

Formula Markup: C21H26N2O3 / HCl

Formula Weight: 390.9

CAS Number: 6211-32-1

Notes: Rauwolscine is a natural alkaloid that acts as a selective and reversible α2-adrenergic receptor antagonist (Ki = 12 nM).{25653} It is a stereoisomer of yohimbine, which potently antagonizes both α1- and α2-adrenergic receptors.{25653} Rauwolscine also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki = 14.3 nM) and as a weak partial agonist at 5-HT1A (IC50 = 1.3 µM).{25654,25657,25652} The α2-adrenergic receptor has diverse physiological functions and antagonists like rauwolscine have numerous applications, including the modulation of mood and behavior.{25656,25655}

• SKU: CAY15596-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 15596-100
• Package Unit: 100 mg
• Quantity Unit: STK