Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]-benzonitrile
Purity: ≥98%
Formula Markup: C22H17F2N5OS
Formula Weight: 437.5
CAS Number: 182760-06-1
Notes: Ravuconazole is an orally available triazole fungicide that potently inhibits the growth of a wide range of fungi (MICs range from 25 to 780 ng/ml).{30389,30390} Like other azoles, ravuconazole inhibits cytochrome P450 (CYP) isoforms that are involved in ergosterol biosynthesis, interfering with the generation of the fungal and protozoan cell membranes.{30388} Ravuconazole specifically inhibits sterol 14α-demethylase (CYP51).{30392,30391} As this enzyme is also important in the development of trypanosomes, ravuconazole is effective against T. cruzi infections in animal models of Chagas disease.{30392,30391}
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