RBFOX1 Polyclonal Antibody

Target Synonym: RBFOX1;2BP1;A2BP1;FOX-1;FOX1;HRNBP1

Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Background: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.

Immunogen: Recombinant fusion protein of human RBFOX1

Dilution: WB 1:500-1:2000;IF 1:100-1:200

Calculated MW: 40kDa/42kDa/44kDa

Observed MW: 45-50KDa

• SKU: ELSE-AB-92804-120
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-92804-120
• Package Unit: 120μL
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunofluorescence, Western Blotting
• Isotype: IgG
• Host: Rabbit
• Conjugate: Unconjugated