Recombinant Carbonic Anhydrase VIII/Car8 Monoclonal Antibody

Target Synonym: Car;RP23-180H;AW546993;RP23-180H12.1;wdl;Cals;Cals1;Car8;Carp;Ca8

Background: The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

Immunogen: Recombinant Mouse Carbonic Anhydrase VIII/CA8 protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: WB 1:500-1:2000;IP 1-4 μL/mg of lysate

Calculated MW: 33 kDa

Observed MW: 36 kDa

• SKU: ELSAN300558P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: AN300558P-100
• Package Unit: 100μL
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting
• Isotype: IgG
• Host: Rabbit
• Conjugate: Unconjugated