Target Synonym: B-Cell-Specific Glycoprotein B;B29;B-Cell Antigen Receptor Complex-Associated Protein Beta Chain;B-Cell-Specific Glycoprotein B29;Igbeta;Ig-beta;Immunoglobulin-Associated B29 Protein;Igb;Cd79b;B29;Ig&beta
Background: CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).
Immunogen: Recombinant Mouse CD79B/Ig-beta Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:200-1:1000
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