Recombinant Human ACVRL1 Protein(His Tag)

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Protein Tag: C-His

Uniprot: P37023

Accession: P37023

Background: This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with an other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine-and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with an other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with an hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Bio Acitivity: Not validated for activity

Sequence: Asp22-Gln118

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 10.5 kDa

Observed MW: 25-30 kDa

• SKU: ELSPDMH100250-500
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100250-500
• Package Unit: 500μg
• Quantity Unit: STK