Recombinant Human BMP6 Protein(Fc Tag)

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Protein Tag: C-Fc

Uniprot: P22004

Accession: P22004

Background: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Bio Acitivity: Not validated for activity

Sequence: Ser375-His513

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 40.2 kDa

Observed MW: 42 kDa

• SKU: ELSPDMH100266-500
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100266-500
• Package Unit: 500μg
• Quantity Unit: STK