Research Areas: Developmental Biology
Uniprot: P12643
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Form: Liquid or Lyophilized powder
Tag Info: N-terminal 6xHis-tagged
Purity: Greater than 90% as determined by SDS-PAGE.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Molecular Weight: 14.9 kDa
Gene Names: BMP2
Organism: Homo sapiens (Human)
Source: Yeast
Expression Region: 283-396aa
Protein Length: Full Length of Mature Protein
Target Protein Sequence: QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
Endotoxin: Not test.
Relevance: Induces cartilage and bone formation.
Reference: Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment.Heng S., Paule S., Hardman B., Li Y., Singh H., Rainczuk A., Stephens A.N., Nie G.Endocrinology 151:3909-3917(2010)
Function: Induces cartilage and bone formation