Recombinant Human CD59 glycoprotein protein (His Tag)

Protein Tag: N-His

Uniprot: P13987

Accession: P13987-1

Background: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Bio Acitivity: Not validated for activity

Sequence: Leu26-Asn102

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 10.2 kDa

Observed MW: 14-16 kDa

• SKU: ELSPDEH100694-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDEH100694-1
• Package Unit: 1mg
• Quantity Unit: STK
• Reactivity: Human
• Host: Escherichia Coli